In 2018,Zeng, Yu; Zheng, Hao-liang; Yang, Zhao; Liu, Cheng-Kou; Fang, Zheng; Guo, Kai published 《Copper(I) Iodide-Catalyzed (Het)arylation of Diethyl Malonate with (Het)aryl Bromides by Using 1,3-Benzoxazole as a Ligand》.Synlett published the findings.Computed Properties of C5H3BrClN The information in the text is summarized as follows:
An efficient Ullmann-type coupling of aryl bromides with di-Et malonate in the presence of copper(I) iodide and 1,3-benzoxazole is presented. This method has a broad substrate scope (heterocyclic and Ph bromides) and good functional-group tolerance (OMe, Me, Ac, CN, NO2, F, and Cl). Moreover, less time is needed to reach full conversion (3-9 h). In the experiment, the researchers used many compounds, for example, 5-Bromo-2-chloropyridine(cas: 53939-30-3Computed Properties of C5H3BrClN)
5-Bromo-2-chloropyridine(cas: 53939-30-3) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Computed Properties of C5H3BrClN