Crystal structures and Hirshfeld surface analysis of a series of 4-O-arylperfluoropyridines was written by Peloquin, Andrew J.;Corley, Cynthia A.;Adas, Sonya K.;Balaich, Gary J.;Iacono, Scott T.. And the article was included in Acta Crystallographica in 2019.Synthetic Route of C5F5N The following contents are mentioned in the article:
Five new crystal structures of perfluoropyridine substituted in the 4-position with phenoxy, 4-bromophenoxy, naphthalen-2-yloxy, 6-bromonaphthalen-2-yloxy, and 4,4′-biphenoxy are reported, viz. 2,3,5,6-tetrafluoro-4-phenoxypyridine, C11H5F4NO (I), 4-(4-bromophenoxy)-2,3,5,6-tetrafluoropyridine, C11H4BrF4NO (II), 2,3,5,6-tetrafluoro-4-[(naphthalen-2-yl)oxy]pyridine, C15H7F4NO (III), 4-[(6-bromonaphthalen-2-yl)oxy]-2,3,5,6-tetrafluoropyridine, C15H6BrF4NO (IV), and 2,2′-bis[(perfluoropyridin-4-yl)oxy]-1,1′-biphenyl, C22H8F8N2O2 (V). The dihedral angles between the aromatic ring systems in I-IV are 78.74 (8), 56.35 (8), 74.30 (7), and 64.34 (19)掳, resp. The complete mol. of V is generated by a crystallog. twofold axis: the dihedral angle between the pyridine ring and adjacent Ph ring is 80.89 (5)掳 and the equivalent angle between the biphenyl rings is 27.30 (5)掳. In each crystal, the packing is driven by C-H路路路F interactions, along with a variety of C-F路路路蟺, C-H路路路蟺, C-Br路路路N, C-H路路路N, and C-Br路路路蟺 contacts. Hirshfeld surface anal. was conducted to aid in the visualization of these various influences on the packing. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Synthetic Route of C5F5N).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the 蟺-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the 蟽 bonds. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Synthetic Route of C5F5N