Thiophilic ring opening reactions of 3,3-bis(trifluoromethyl)-5-alkoxy-1,2-dithiolanes under action of nucleophiles was written by Petrov, Viacheslav. And the article was included in Journal of Fluorine Chemistry in 2018.Computed Properties of C5F5N The following contents are mentioned in the article:
The reaction of 3,3-bis(trifluoromethyl)-5-alkoxy-1,2-dithiolanes (RO = OEt or OBu-n) proceeds through thiophilic attack of BuLi leading to the formation of ring-opened product BuSCH(OR)CH2C(CF3)2SLi, which can be converted into the corresponding thiols or sulfides by the reaction with H+ or alkyl halide. Interaction of 3,3-bis(trifluoromethyl)-5-n-butoxy-1,2-dithiolane with CF3Si(CH3)3 resulted in unusual reaction leading to the formation of CF3SCH(OBu)CH2C(CF3)=CF2. The treatment of CF3SCH(OBu)CH2C(CF3)=CF2 with CsF in the presence pentafluoropyridine led to equimolar mixture of 2-n-butoxy-1,1-bis(trifluoromethyl)cyclopropane and 4-(trifluoromethylthio)tetrafluoropyridine (as a result of interception of liberated in this process CF3CF3S–anion by pentafluoropyridine). This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Computed Properties of C5F5N).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Computed Properties of C5F5N