Visible-light-mediated amidation from carboxylic acids and tertiary amines via C-N cleavage was written by Gu, Chengyihan;Wang, Shuaishuai;Zhang, Qingran;Xie, Jin. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2022.Related Products of 700-16-3 The following contents are mentioned in the article:
Synthesis of tertiary amides RC(O)NR1R2 [R = Ph, 4-MeC6H4, 4-PhC6H4, etc.; R1 = R2 = Et, n-Pr; R1R2 = CH2(CH2)3CH2] via iridium photocatalyzed amidation of carboxylic acids and tertiary amines through C-N bond cleavage was reported. A wide scope of structurally diverse carboxylic acids participated smoothly in the reaction, providing the desired tertiary amides with moderate-to-good yields (up to 93% yield). This amidation strategy provided an alternative way to address the regioselectivity between nucleophilic functional groups, thus complementing the functional group compatibility of classical amidation protocols. Its synthetic robustness was also proved by the late-stage modification of several complex mols. and gram-scale applications. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Related Products of 700-16-3).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C鈥揌 in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Related Products of 700-16-3