Perfluoropyridine as an Efficient, Tunable Scaffold for Bis(pyrazol-1-yl)pyridine Copper Complexes was written by Peloquin, Andrew J.;Houck, Matthew B.;McMillen, Colin D.;Iacono, Scott T.;Pennington, William T.. And the article was included in European Journal of Inorganic Chemistry in 2020.Reference of 700-16-3 The following contents are mentioned in the article:
This report details the syntheses of five new 2,6-bis(pyrazol-1-yl)pyridine ligands carried out by a unique strategy of using pentafluoropyridine for the pyridine core. Formation of each ligand is accomplished under mild conditions using carbonate bases. Each ligand reacts readily with copper(II) triflate to form the corresponding salt in high yield. Ligands and complexes were characterized by a combination of multi-nuclear NMR, FTIR, UV/visible, and single-crystal x-ray diffraction. Copper(II) triflate complexes demonstrating addnl. coordination modes of this multi-pyrazole ligand system were also obtained. Despite the electron withdrawing nature of fluorine, the coordination parameters of the new complexes are comparable to previous pyrazole-based complexes. This synthetic methodol. provides efficient entry to a previously difficult to access ligand system. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Reference of 700-16-3).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six 蟺 electrons that are delocalized over the ring. The molecule is planar and, thus, follows the H眉ckel criteria for aromatic systems. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Reference of 700-16-3