Reactions of Fluoroalkanes with Mg-Mg Bonds: Scope, sp3C-F/sp2C-F Coupling and Mechanism was written by Coates, Greg;Ward, Bryan J.;Bakewell, Clare;White, Andrew J. P.;Crimmin, Mark R.. And the article was included in Chemistry – A European Journal in 2018.Product Details of 700-16-3 The following contents are mentioned in the article:
Sp3C-F Bonds of fluoroalkanes (7 examples; 1æ? 2æ?and 3æ? undergo addition to a low-valent Mg-Mg species generating reactive organomagnesium reagents. Further reactions with a series of electrophiles results in a net C-F to C-B, C-Si, C-Sn or C-C bond transformation (11 examples, diversity). The new reactivity was exploited in an unprecedented one-pot magnesium-mediated coupling of sp3C-F and sp2C-F bonds. Calculations suggest that the sp3C-F bond activation step occurs by frontside nucleophilic attack of the Mg-Mg reagent on the fluoroalkane. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Product Details of 700-16-3).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Product Details of 700-16-3