Organocatalyzed Fluoride Metathesis was written by Mulryan, Daniel;White, Andrew J. P.;Crimmin, Mark R.. And the article was included in Organic Letters in 2020.Name: 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:
A new organocatalyzed fluoride metathesis reaction between fluoroarenes and carbonyl derivatives is reported. The reaction exchanges fluoride (F–) and alternate nucleophiles (OAc–, OCO2R–, SR–, Cl–, CN–, NCS–). The approach provides a conceptually novel route to manipulate the fluorine content of organic mols. When the fluorination and defluorination steps are combined into a single catalytic cycle, a byproduct free and 100% atom-efficient reaction can be achieved. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Name: 2,3,4,5,6-Perfluoropyridine).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six è?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hçckel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule ä¼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Name: 2,3,4,5,6-Perfluoropyridine