Direct C-H Multifluoroarylation of Ethers through Hydrogen Atom Transfer Using Photoredox Catalysis was written by Wang, Junlei;Huang, Binbin;Gao, Yuan;Yang, Chao;Xia, Wujiong. And the article was included in Journal of Organic Chemistry in 2019.Application In Synthesis of 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:
A direct defluorinative multifluoroarylation of unactivated sp3 C-H bonds through hydrogen atom transfer using photoredox catalysis has been developed. The C(sp3)-C(sp2) couplings between C(sp2)-F bonds and corresponding C(sp3)-H bonds adjacent to heteroatoms proceeded smoothly to afford the desired products in moderate to good yields. Preliminary mechanistic investigations on this novel transformation revealed that the C-H cleavage process might be involved in the rate-determining step. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Application In Synthesis of 2,3,4,5,6-Perfluoropyridine).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Application In Synthesis of 2,3,4,5,6-Perfluoropyridine