A Selective Single Step Amidation of Polyfluoroarenes was written by Noel, Alyssa M.;Hamilton, Matthew;Keen, Brockton;Despain, Megan;Day, Jon;Weaver, Jimmie D.. And the article was included in Journal of Fluorine Chemistry in 2021.Quality Control of 2,3,4,5,6-Perfluoropyridine The following contents are mentioned in the article:
Herein, good yields of N-polyfluoroaryl acid amides RC(O)NHR1 (R = Me, CF3; R1 = 2,3-difluoro-4-nitrophenyl, heptafluoronaphthalen-2-yl, pyridin-2-yl, etc.) were achieved in a single step under mild reaction conditions. Key to achieving optimal yields is the use of two equivalent of the nucleophile RC(O)NH2. In addition, the mechanism of the reaction is discussed which has implications for other related nucleophilic substitutions. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Quality Control of 2,3,4,5,6-Perfluoropyridine).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of é?8.7 è?10é? cm3è·¯molé?.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJè·¯molé? in the liquid phase and 140.4 kJè·¯molé? in the gas phase. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Quality Control of 2,3,4,5,6-Perfluoropyridine