Activation of Aromatic C-F Bonds by a N-Heterocyclic Olefin (NHO) was written by Mandal, Debdeep;Chandra, Shubhadeep;Neuman, Nicolas I.;Mahata, Alok;Sarkar, Arighna;Kundu, Abhinanda;Anga, Srinivas;Rawat, Hemant;Schulzke, Carola;Mote, Kaustubh R.;Sarkar, Biprajit;Chandrasekhar, Vadapalli;Jana, Anukul. And the article was included in Chemistry – A European Journal in 2020.Reference of 700-16-3 The following contents are mentioned in the article:
An N-heterocyclic olefin (NHO) such as 1,3,4,5-tetramethyl-2-methyleneimidazoline, a terminal alkene selectively activates aromatic C-F bonds without the need of any addnl. catalyst. As a result, a straightforward methodol. was developed for the formation of different fluoroaryl-substituted alkenes I (R = pentafluorophenyl, tetrafluoropyridin-4-yl, heptafluoronaphthalen-2-yl, etc.) in which the central carbon-carbon double bond is in a twisted geometry. This study involved multiple reactions and reactants, such as 2,3,4,5,6-Perfluoropyridine (cas: 700-16-3Reference of 700-16-3).
2,3,4,5,6-Perfluoropyridine (cas: 700-16-3) belongs to pyridine derivatives. Pyridine has a conjugated system of six è?electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hçckel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule ä¼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Reference of 700-16-3