Synthesis of functionalized 3-pyridyl methyl ketones was written by Wright, S. W.;Hageman, D. L.;McClure, L. D.. And the article was included in Journal of Heterocyclic Chemistry in 1998.Safety of N-(5-Bromopyridin-2-yl)-4-methylbenzenesulfonamide The following contents are mentioned in the article:
A synthesis of 3-pyridyl Me ketones is described that employs a Pd-catalyzed olefination of 3-bromopyridines with Bu vinyl ether followed by acid hydrolysis of the intermediate pyridyl vinyl ether in situ. This method was applied to bromoquinoline substrates as well. The reaction is compatible with a variety of functional groups. This study involved multiple reactions and reactants, such as N-(5-Bromopyridin-2-yl)-4-methylbenzenesulfonamide (cas: 207801-52-3Safety of N-(5-Bromopyridin-2-yl)-4-methylbenzenesulfonamide).
N-(5-Bromopyridin-2-yl)-4-methylbenzenesulfonamide (cas: 207801-52-3) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.Safety of N-(5-Bromopyridin-2-yl)-4-methylbenzenesulfonamide