Rosenberg, Adam J. published the artcileSynthesis of Imidazo[4,5-b]pyridines and Imidazo[4,5-b]pyrazines by Palladium Catalyzed Amidation of 2-Chloro-3-amino-heterocycles, Application In Synthesis of 133627-45-9, the main research area is heterocyclic compound imidazopyridine imidazopyrazine preparation; pentosidine natural product model system preparation; mutagen phenylimidazopyridinamine methyl preparation; carboxylic amide coupling reaction chloropyridine chloropyrazine.
A facile synthesis of imidazo[4,5-b]pyridines and -pyrazines is described using a Pd-catalyzed amide coupling reaction. This reaction provides quick access to products with substitution at N1 and C2. A model system relevant to the natural product pentosidine (I) has been demonstrated, as well as the total synthesis of the mutagen 1-Me-5-PhIP (II).
Organic Letters published new progress about Cross-coupling reaction. 133627-45-9 belongs to class pyridine-derivatives, name is 2-Chloro-4-methylpyridin-3-amine, and the molecular formula is C6H7ClN2, Application In Synthesis of 133627-45-9.