Murphy, Rebecca A. published the artcileDirect Methoxypyridine Functionalization Approach to Magellanine-Type Lycopodium Alkaloids, Application of 2-Methoxynicotinaldehyde, the main research area is enantioselective synthesis tetracyclic core magellanine Lycopodium alkaloid; Hajos Parrish reaction enantioselective synthesis magellanine Lycopodium alkaloid; palladium catalyzed pyridine functionalization enantioselective synthesis magellanine Lycopodium alkaloid.
A concise enantioselective approach to the tetracyclic core of the magellanine-type Lycopodium alkaloids is reported. Key to this approach is the use of the Hajos-Parrish reaction to set a challenging quaternary stereocenter, thereby guiding the stereoselectivity for the remainder of the synthesis, as well as the use of a palladium-mediated direct pyridine functionalization reaction to forge the tetracyclic core.
Organic Letters published new progress about Alkaloids Role: SPN (Synthetic Preparation), PREP (Preparation) (Lycopodium). 71255-09-9 belongs to class pyridine-derivatives, name is 2-Methoxynicotinaldehyde, and the molecular formula is C7H7NO2, Application of 2-Methoxynicotinaldehyde.