Savarimuthu, Sebastian Antony published the artcileSodium Tertiary Pentoxide as a Mild and Efficient Base to Make C-C Bond between Acetylenes and Aldehydes (or) Ketones Producing Propargyl Alcohols, COA of Formula: C7H7NO2, the main research area is carbonyl compound phenylacetylene sodium tertiary pentoxide promoter green coupling; propargyl alc preparation.
This report confirmed that sodium tertiary-pentoxide was a very effective base for the nucleophilic addition of acetylenes to aldehydes and ketones in 1,4-dioxane at room temperature These mild and operationally simple procedures were working well with a variety of aromatic and heteroaromatic aldehydes and also equally working well with aliphatic, aromatic and heteroaromatic ketones. A very clean product of secondary and tertiary propargylic alcs. were obtained from 70-94% yield. This process was explored in bulk scale synthesis on selected mols. and also adapted the column free purification for most of the substrates.
ChemistrySelect published new progress about Alcohols, propargyl Role: SPN (Synthetic Preparation), PREP (Preparation). 71255-09-9 belongs to class pyridine-derivatives, name is 2-Methoxynicotinaldehyde, and the molecular formula is C7H7NO2, COA of Formula: C7H7NO2.