Grozinger, K. G. published the artcileSynthesis of nevirapine and its major metabolite, COA of Formula: C6H7ClN2, the main research area is nevirapine preparation metabolite.
Several synthetic methods were developed during the process optimization for the large scale synthesis of nevirapine, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. The synthesis of its putative major metabolite 11-cyclopropyl-5,11-dihydro-4-hydroxymethyl-6H-[3,2-b:2′,3′-e][1,4]diazepin-6-one and its oxidation to the corresponding aldehyde, were described.
Journal of Heterocyclic Chemistry published new progress about nevirapine preparation metabolite. 133627-45-9 belongs to class pyridine-derivatives, name is 2-Chloro-4-methylpyridin-3-amine, and the molecular formula is C6H7ClN2, COA of Formula: C6H7ClN2.