Analyzing the synthesis route of 102368-13-8

According to the analysis of related databases, 102368-13-8, the application of this compound in the production field has become more and more popular.

Related Products of 102368-13-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 102368-13-8, name is 1,1′-Thiocarbonylbis(pyridin-2(1H)-one). This compound has unique chemical properties. The synthetic route is as follows.

Example 74 1-(2-Azidoethoxy)-4-isothiocyanatomethyl-2-methoxy Benzene (34) A solution of 33 (0.115 g, 0.33 mmol) in DMF (1.5 mL) was treated with NEt3 (0.037 g, 0.36 mmol) and stirred for 1 h. The mixture was treated with 1,1-thiocarbonyl di-2(1H)-pyridone (0.084 g, 0.33 mmol) and stirred for 2.5 h at room temperature. The mixture was diluted with H2O and extracted with diethyl ether several times. The combined organic layer was washed with H2O and bnine, dried over MgSO4 and concentrated in vacuo. The residue was purified by flash column chromatography over silica gel using EtOAc:Hex (1:2) as eluant to give 34 as oil (0.065 g, 74%) 1H NMR (CDCl3) delta 6.75-6.91 (m, 3H, Ar), 4.65 (s, 2H, CH2N=C=S), 4.20 (t, 2H, OCH2), 3.90 (s, 3H, OCH3), 3.62 (t, 211, CH2N3)

According to the analysis of related databases, 102368-13-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Pacific Corporation; Digital Biotech Co., Ltd.; US6476076; (2002); B1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem