Lee, Jongkook’s team published research in Bioorganic & Medicinal Chemistry Letters in 22 | CAS: 197958-29-5

Bioorganic & Medicinal Chemistry Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Recommanded Product: 2-Pyridinylboronic acid.

Lee, Jongkook published the artcileSynthesis and structure-activity relationship of aminopyridines with substituted benzoxazoles as c-Met kinase inhibitors, Recommanded Product: 2-Pyridinylboronic acid, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(12), 4044-4048, database is CAplus and MEDLINE.

A series of hydroxybenzoxazole derivatives, e.g., I [R2 = H, Cl, MeNH, MeCONH, R3 = H, MeCO, Me(OH)CH, 3-pyrazolyl, etc., R4 = H, 2-pyridinyl, 4-MeOC6H4, Me2CHNH], was synthesized, and their c-Met kinase inhibitory activity was evaluated. Described herein is a potent c-Met inhibitor by structural modification of the parent benzoxazole scaffold, with particular focus on the hydroxyl substituent of the benzoxazole moiety.

Bioorganic & Medicinal Chemistry Letters published new progress about 197958-29-5. 197958-29-5 belongs to pyridine-derivatives, auxiliary class Pyridine,Boronic acid and ester, name is 2-Pyridinylboronic acid, and the molecular formula is C5H6BNO2, Recommanded Product: 2-Pyridinylboronic acid.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem