Rozatian, Neshat published the artcileKinetics of Electrophilic Fluorination of Steroids and Epimerisation of Fluorosteroids, Category: pyridine-derivatives, the publication is Chemistry – A European Journal (2020), 26(52), 12027-12035, database is CAplus and MEDLINE.
Fluorinated steroids, which are synthesized by electrophilic fluorination, form a significant proportion of marketed pharmaceuticals. To gain quant. information on fluorination at the 6-position of steroids, kinetics studies were conducted on enol ester derivatives of progesterone, testosterone, cholestenone and hydrocortisone with a series of electrophilic N-F reagents. The stereoselectivities of fluorination reactions of progesterone enol acetate and the kinetic effects of additives, including methanol and water, were investigated. The kinetics of epimerization of 6β-fluoroprogesterone to the more pharmacol. active 6α-fluoroprogesterone isomer in HCl/acetic acid solutions are detailed.
Chemistry – A European Journal published new progress about 107263-95-6. 107263-95-6 belongs to pyridine-derivatives, auxiliary class Fluorination reagent, name is 1-Fluoropyridiniumtriflate, and the molecular formula is C6H5F4NO3S, Category: pyridine-derivatives.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem