Yuan, Yu-Chang’s team published research in Journal of Organic Chemistry in 86 | CAS: 91-02-1

Journal of Organic Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C8H14O2, Computed Properties of 91-02-1.

Yuan, Yu-Chang published the artcileMetal-Free Catalyzed Synthesis of Fluorescent Indolizine Derivatives, Computed Properties of 91-02-1, the publication is Journal of Organic Chemistry (2021), 86(18), 12737-12744, database is CAplus and MEDLINE.

A mild and high efficient method to prepare indolizines such as I [R = H, Me; R1 = Me, Ph, CH2CH2CO2Et; R2 = H, Me, OEt; R3 = Me, Ph, 4-ClC6H4; R1R2 = (CH2)3] by two-component reaction with the acid as the catalyst was developed. In this reaction, a new ring efficiently formed in one-step reaction. A wide range of substrates could be applied and the desired products were obtained in 8-95% yields under metal-free conditions. Different indolizine derivatives I were synthesized by general conditions and microwave irradiation conditions, and compound I [R = H, R1 = Me, R2 = H, R3 = Ph] gave the best results with an isolated yield of 95% and 82%, resp. The structures of synthesized compounds I were characterized by spectral anal., and compound I [R = H, R1R2 = (CH2)3, R3 = 4-ClC6H4] was confirmed by single crystal X-ray anal. UV-vis absorption and fluorescence properties of these compounds I were correlated with substituent groups on indolizine rings.

Journal of Organic Chemistry published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C8H14O2, Computed Properties of 91-02-1.

Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem