Ross, John H.’s team published research in Drug and Chemical Toxicology (1977) in 1979-09-30 | CAS: 36437-30-6

Drug and Chemical Toxicology (1977) published new progress about Adrenal gland. 36437-30-6 belongs to class pyridine-derivatives, name is 1,1-Di-n-octyl-4,4-bipyridinium Dibromide, and the molecular formula is C26H42Br2N2, COA of Formula: C26H42Br2N2.

Ross, John H. published the artcileToxicity of 1,1′-alkyl-4,4′-bipyridylium salts in the rat, COA of Formula: C26H42Br2N2, the main research area is alkylbipyridylium toxicity; bipyridylium alkyl toxicity.

Viologens (I, R = Me or Ph; n = 1-7) were administered s.c. to female Sprague-Dawley rats to determine relative toxicities. I produced the spectrum of effects previously reported for paraquat and a focal necrosis at the injection site, nonemptying of the stomach, and adrenal enlargement. A LD of Pr, hexyl, or benzyl viologen often produced a yellow to red serous fluid in the pleural cavity. Many of the signs observed with I poisoning are similar to adrenal hormone effects which may be contributing to the toxicity.

Drug and Chemical Toxicology (1977) published new progress about Adrenal gland. 36437-30-6 belongs to class pyridine-derivatives, name is 1,1-Di-n-octyl-4,4-bipyridinium Dibromide, and the molecular formula is C26H42Br2N2, COA of Formula: C26H42Br2N2.

Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem