Liu, Xiaoxi published the artcileRegulating Molecular Recognition with C-Shaped Strips Attained by Chirality-Assisted Synthesis, Safety of 1,1-Di-n-octyl-4,4-bipyridinium Dibromide, the main research area is chirality assisted synthesis mol recognition mol shape strip; chirality-assisted synthesis; cooperative effects; host-guest interactions; shape control; supramolecular chemistry.
Chirality-assisted synthesis (CAS) is a general approach to control the shapes of large mol. strips. CAS is based on enantiomerically pure building blocks that are designed to strictly couple in a single geometric orientation. Fully shape-persistent structures can thus be created, even in the form of linear chains. With CAS, selective recognition between large host and guest mols. can reliably be designed de novo. To demonstrate this concept, three C-shaped strips that can embrace a pillar[5]arene macrocycle were synthesized. The pillar[5]arene bound to the strips was a better host for electron-deficient guests than the free macrocycle. Exptl. and computational evidence is provided for these unique cooperative interactions to illustrate how CAS could open the door towards the precise positioning of functional groups for regulated supramol. recognition and catalysis.
Angewandte Chemie, International Edition published new progress about Chirality. 36437-30-6 belongs to class pyridine-derivatives, name is 1,1-Di-n-octyl-4,4-bipyridinium Dibromide, and the molecular formula is C26H42Br2N2, Safety of 1,1-Di-n-octyl-4,4-bipyridinium Dibromide.