Sources of common compounds: 2-Chloro-3-fluoro-4-hydroxypyridine

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1184172-46-0, 2-Chloro-3-fluoro-4-hydroxypyridine.

Related Products of 1184172-46-0, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1184172-46-0, name is 2-Chloro-3-fluoro-4-hydroxypyridine, molecular formula is C5H3ClFNO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

2-Chloro-3-fluoro-4-hydroxypyridine (10 mmol), methyl iodide (20 mmol) and potassium carbonate (20 mmol) in acetone (100 ml) was refluxed overnight. The inorganic salt was filtered and the solvent was evaporated. The residue was purified on column (eluent: ethyl acetate: hexane = 1 :5) to afford a colorless liquid (52%).

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 1184172-46-0, 2-Chloro-3-fluoro-4-hydroxypyridine.

Reference:
Patent; BTG INTERNATIONAL LIMITED; WO2009/103950; (2009); A1;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem