Beier, Markus published the artcileNucleotides. Part 62. Pyridinium salts. An effective class of catalysts for oligonucleotide synthesis, Related Products of pyridine-derivatives, the publication is Helvetica Chimica Acta (1999), 82(6), 879-887, database is CAplus.
Various pyridinium salts were tested as catalysts for the condensation step in the phosphoramidite approach of oligonucleotide synthesis. Pyridinium chloride turned out to be the most effective activator, speeding up the condensation tremendously. Pyridinium bromide and tosylate can also he regarded as powerful substitutes for the commonly used 1H-tetrazole. The acidic pKa of the pyridinium cation provides an optimal range for phosphoramidite activation, which is followed by a nucleophilic attack of the pyridine ring to give a P-pyridinio intermediate as the most likely precursor of phosphite ester formation. 31P-NMR studies indirectly support this proposal.
Helvetica Chimica Acta published new progress about 636-73-7. 636-73-7 belongs to pyridine-derivatives, auxiliary class Pyridine,Sulfonic acid, name is Pyridine-3-sulfonic acid, and the molecular formula is C5H5NO3S, Related Products of pyridine-derivatives.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem