Singh, Anmol published the artcileComparative study of palladium(II) complexes bearing tridentate ONS and NNS Schiff base ligands: Synthesis, characterization, DFT calculation, DNA binding, bioactivities, catalytic activity, and molecular docking, Application In Synthesis of 91-02-1, the publication is Polyhedron (2022), 115895, database is CAplus.
Two palladium (II) Schiff base complexes were prepared by using equivalent molar of Schiff base ligand [L1 = (E)-2-(((2-(benzylthio)phenyl)imino)methyl)naphthalen-1-ol and L2 = (E)-N-(2-(benzylthio)phenyl)-1-phenyl-1-(pyridin-2-yl)methanimine] and sodium tetrachloropalladate. The structure of ligands and complexes were characterized by physicochem. and spectroscopic analyses. The results suggested that the Pd(II) complexes have a distorted square planar geometry when coordinated to the tridentate ONS from L1 and the NNS donor ligand from L2. Electronic absorption and spectrofluorometric measurements were employed to investigate the DNA binding of ligands and their associated complexes with CT-DNA. DFT calculations were used to optimize the geometric structures and calculate the electronic and structural properties of the synthesized compounds NBO anal. was also performed in combination with the TD-DFT method. Moreover, to study the reactivity and bioactivity, the synthesized compounds were tested for in-vitro antioxidant activity by utilizing the DPPH method, in-vitro anti-inflammatory activity using protein denaturation method, and in-vitro anti-diabetic activity employing α-glucosidase and α-amylase enzymes. The results reflect that PdL1 is more biol. potent than PdL2 or other related palladium complexes, as discussed in the literature. The binding mechanism of the synthesized compounds with CT-DNA, α-glucosidase, and α-amylase, was investigated using mol. docking experiments In addition to these, the catalytic activity of palladium metal complexes (PdL1 and PdL2) was evaluated for the Suzuki-Miyaura reaction for comparisons.
Polyhedron published new progress about 91-02-1. 91-02-1 belongs to pyridine-derivatives, auxiliary class Pyridine,Benzene,Ketone, name is Phenyl(pyridin-2-yl)methanone, and the molecular formula is C13H16BF3O2S, Application In Synthesis of 91-02-1.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem