In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 141-86-6, name is 2,6-Diaminopyridine, the common compound, a new synthetic route is introduced below. name: 2,6-Diaminopyridine
N,N’-(pyridine-2,6-diyl)bis(2,2-dimethylpropanamide) (S17). Trimethylacetyl chloride (4.40mL, 36 mmol) was added to a stirred solution of 2,6 diaminopyridine (1.64 g, 15 mmol) andtriethylamine (6.30 mL, 45 mmol) in dichloromethane at 0 C. The solution was allowed to stir atroom temperature for 21 hours. The reaction mixture was washed with water and back extractedwith dichloromethane. The product was purified by column chromatography eluting with 20%ethyl acetate/hexanes to yield S17 (3.67, 13.2 mmol, 88%) as a light yellow solid.Rf: 0.28 (20% ethyl acetate/hexanes).1H NMR (600 MHz, CDCl3): delta =7.92 (d, J = 8.1 Hz, 2H), 7.73 (s, 2H), 7.69 (t, J = 8.1 Hz, 1H),1.32 (s, 18H)13C NMR (150 MHz, CDCl3): delta = 176.9, 149.8, 140.9, 109.5, 39.9, 27.6
The synthetic route of 141-86-6 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Fosu, Stacy C.; Hambira, Chido M.; Chen, Andrew D.; Fuchs, James R.; Nagib, David A.; Chem; vol. 5; 2; (2019); p. 417 – 428;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem