Liu, Xin published the artcileSelective Construction of C-C and C=C Bonds by Manganese Catalyzed Coupling of Alcohols with Phosphorus Ylides, Recommanded Product: 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, the publication is Advanced Synthesis & Catalysis (2021), 363(4), 1096-1104, database is CAplus.
The manganese complex e.g., I catalyzed coupling of alcs. ROH (R = benzyl, cyclohexyl, furan-2-ylmethyl, etc.) with phosphorus ylides R1 = P(C6H5)3 (I) [R1 = H, C(O)OEt, (morpholin-4-yl)carbonyl, benzoyl, etc.] were reported. The selectivity in the coupling of primary alcs. with phosphorus ylides (I) to form carbon-carbon single (C-C) and carbon-carbon double (C=C) bonds can be controlled by the ligands. In the conversion of more challenging secondary alcs. with phosphorus ylides (I), the selectivity towards the formation of C-C vs is obtained. C=C bonds can be controlled by the reaction conditions, namely the amount of base. The scope and limitations of the coupling reactions were thoroughly evaluated by the conversion of 21 alcs. and 15 ylides. Notably, compared to existing methods, which are based on precious metal complexes as catalysts, the present catalytic system is based on earth abundant manganese catalysts e.g., I. The reaction can also be performed in a sequential one-pot reaction generating the phosphorus ylide in situ followed manganese catalyzed C-C and C=C bond formation. Mechanistic studies suggest that the C-C bond was generated via a borrowing hydrogen pathway and the C=C bond formation followed an acceptorless dehydrogenative coupling pathway.
Advanced Synthesis & Catalysis published new progress about 338800-13-8. 338800-13-8 belongs to pyridine-derivatives, auxiliary class Bis-phosphine Ligands, name is 2,6-Bis((di-tert-butylphosphino)methyl)pyridine, and the molecular formula is C23H43NP2, Recommanded Product: 2,6-Bis((di-tert-butylphosphino)methyl)pyridine.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem