Luise, Nicola published the artcileDiversity-oriented synthesis of bicyclic fragments containing privileged azines, Safety of Ethyl 2-(2-chloropyridin-3-yl)acetate, the publication is Bioorganic & Medicinal Chemistry Letters (2019), 29(2), 248-251, database is CAplus and MEDLINE.
An innovative and efficient reagent- and scaffold-based diversity oriented synthesis (DOS) of a fragment set was developed for fragment-based drug discovery (FBDD) programs. Twelve diverse, functionalized and bicyclic scaffolds were rapidly accessed by adopting a convenient synthetic toolkit around three privileged azine cores in order to effectively modulate biomols. These structures are characterized by both key motifs for interacting with diverse biol. targets via hydrogen bonds and useful points of growth for subsequent fragment optimization.
Bioorganic & Medicinal Chemistry Letters published new progress about 164464-60-2. 164464-60-2 belongs to pyridine-derivatives, auxiliary class Pyridine,Chloride,Ester, name is Ethyl 2-(2-chloropyridin-3-yl)acetate, and the molecular formula is C9H10ClNO2, Safety of Ethyl 2-(2-chloropyridin-3-yl)acetate.
Referemce:
https://en.wikipedia.org/wiki/Pyridine,
Pyridine | C5H5N – PubChem