Application of 60032-57-7, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 60032-57-7, name is 2-Methylnicotinaldehyde. This compound has unique chemical properties. The synthetic route is as follows.
In accordance with the process of the present invention, the compound represented by the formula V is first obtained by reacting a compound of the formula VI with a compound of the formula VII to give a compound of the formula V, wherein the compound represented by the formula VI (p-bromochlorobenzene) Add to the reactor, in the argon protection, adding anhydrous tetrahydrofuran as a solvent, cooled to -75 C, slowly dropping 1.5 M 2M butyl lithium solution, reaction, 6 hours, adding anhydrous methanol quenched by adding two The organic layer was dried over anhydrous sodium sulfate and dried. After the dried intermediate, palladium acetate and an appropriate amount of anhydrous potassium acetate were directly added. The reaction was continued for 11 hours, followed by spotting. After the completion of the reaction, Dichloromethane extraction, organic layer dried with anhydrous sodium sulfate and dried, with methylene chloride / petroleum ether (volume ratio of 1: 5) through the column, spin-dried 4-azafluorenone
According to the analysis of related databases, 60032-57-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BOE Technology Group Co., Ltd; Hefei Xin Sheng Photoelectric Technology Co., Ltd; Chen, Jian; Lu, Xiangwan; Li, bin; Zhu, Tao; Yuan, Huifang; Tang, Wenhao; Fang, Qun; Yin, Haibin; Dong, Anxin; (15 pag.)CN105440024; (2016); A;,
Pyridine – Wikipedia,
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