Ir(III)-catalyzed C-H alkynylation of arenes under chelation assistance was written by Tang, Guo-Dong;Pan, Cheng-Ling;Xie, Fang. And the article was included in Organic & Biomolecular Chemistry in 2016.SDS of cas: 4783-68-0 This article mentions the following:
An efficient and mild Ir(III)-catalyzed, chelation assisted C-H alkynation of arenes, e.g., I has been developed using hypervalent iodine alkynes II (R = t-Bu, TIPS, TES, TBDPS) as alkynylating reagents. A broad scope of N-phenyl-2-aminopyridines and 2-phenoxypyridines has been established as effective substrates for this C-H functionalization and the desired alkynylated products, e.g., III are isolated in moderate to high yields. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0SDS of cas: 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.SDS of cas: 4783-68-0