Synthesis of novel tetrahydroisoquinoline bronchodilators was written by Dalence-Guzman, Maria F.;Toftered, Joergen;Oltner, Viveca Thornqvist;Wensbo, David;Johansson, Martin H.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2010.Name: 2-Bromo-5-(methylsulfonyl)pyridine This article mentions the following:
The synthesis and bronchorelaxing effects of a series of novel tetrahydroisoquinoline amides are described. The compounds were evaluated for their ability to relax LTD4 contracted isolated human small airways ex-vivo. Several compounds demonstrated highly efficacious bronchorelaxing properties. Cinnamide I was selected for further studies and constitutes a promising candidate as a novel bronchorelaxing agent for the treatment of pulmonary disorders. In the experiment, the researchers used many compounds, for example, 2-Bromo-5-(methylsulfonyl)pyridine (cas: 343262-51-1Name: 2-Bromo-5-(methylsulfonyl)pyridine).
2-Bromo-5-(methylsulfonyl)pyridine (cas: 343262-51-1) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Name: 2-Bromo-5-(methylsulfonyl)pyridine