Simple exploration of 5-Bromopyridine-2-sulfonyl chloride

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 874959-68-9, 5-Bromopyridine-2-sulfonyl chloride, other downstream synthetic routes, hurry up and to see.

Electric Literature of 874959-68-9, Adding some certain compound to certain chemical reactions, such as: 874959-68-9, name is 5-Bromopyridine-2-sulfonyl chloride,molecular formula is C5H3BrClNO2S, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 874959-68-9.

[(2,2-Dimethyl-1 ,3-dioxolan-4-yl)methyl]amine (0.76ml, 5.85mmol), 5-bromo-2- pyridinesulfonyl chloride (1g, 3.9mmol), DIPEA (1.3ml, 7.8mmol), were stirred together in DCM (20ml) at room temperature under N2 for 1 h. The reaction mixture was extracted with sodium bicarbonate (20ml) dried on a phase separator and reduced under vacuum to give the title compound as a yellow solid ( 0.629g) MH+ 351/353, rt = 2.58 min

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 874959-68-9, 5-Bromopyridine-2-sulfonyl chloride, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; GLAXO GROUP LIMITED; WO2008/145688; (2008); A2;,
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem