Rhodium(III)-catalyzed sp2 C-H bond addition to CF3-substituted unsaturated ketones was written by Jiang, Quanbin;Guo, Tenglong;Wu, Kaikai;Yu, Zhengkun. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2016.Formula: C12H11N This article mentions the following:
Rhodium(III)-catalyzed conjugate addition of aromatic and olefinic C-H bonds to CF3-substituted unsaturated ketones was efficiently achieved. Both arene and olefin substrates bearing a chelate assisted-directing group were coupled with a variety of β-trifluoromethyl-α,β-unsaturated ketones with excellent atom-economy, high yields and broad substrate scopes. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Formula: C12H11N).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Formula: C12H11N