Palladium-Catalyzed Regioselective C-H Acetoxylation of 2-Aryloxypyridines with 2-Pyridyloxy as a Removable Directing Group was written by Wang, Liang;Pan, Liang;Huang, Yibo;Chen, Qun;He, Mingyang. And the article was included in European Journal of Organic Chemistry in 2016.Quality Control of 2-Phenoxypyridine This article mentions the following:
A simple and regioselective palladium-catalyzed ortho-C(sp2)-H acetoxylation of 2-aryloxypyridines with PhI(OAc)2 as both the oxidant and acetate source has been developed. The mono- and di-acetoxylated products can be achieved by tuning the equivalent of PhI(OAc)2 and the reaction temperature A wide range of 2-aryloxypyridines is tolerated. Moreover, 2-pyridyloxyl and acetyl groups can be easily removed, which provides straightforward access to poly-substituted phenols. In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0Quality Control of 2-Phenoxypyridine).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Quality Control of 2-Phenoxypyridine