Ethyl 2-bromoisonicotinate (cas: 89978-52-9) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application In Synthesis of Ethyl 2-bromoisonicotinate
Synthesis and biological evaluation of 4-carbamoyl-2-β-D-ribofuranosylpyridine was written by Joos, Pieter E.;Esmans, Eddy L.;Dommisse, Roger A.;Van Dongen, Walter;Lepoivre, Jozef A.;Alderweireldt, Frank C.;Balzarini, Jan;De Clercq, Erik. And the article was included in Nucleosides & Nucleotides in 1991.Application In Synthesis of Ethyl 2-bromoisonicotinate This article mentions the following:
The biol. evaluation and preparation of the title compound (I) and it α-anomer from 2-amino-4-methylpyridine, via addition reaction of lithio(dimethyloxazolinyl)pyridine II with 2,4:3,5-di-O-benzylidenealdehydo-D-ribose (III), are reported. I showed no appreciable virucidal activity and was a weak cytostatic agent in a number of tumor cell systems. In the experiment, the researchers used many compounds, for example, Ethyl 2-bromoisonicotinate (cas: 89978-52-9Application In Synthesis of Ethyl 2-bromoisonicotinate).
Ethyl 2-bromoisonicotinate (cas: 89978-52-9) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine groups exist in countless molecules, and their applications include catalysis, drug design, molecular recognition, and natural product synthesis.Application In Synthesis of Ethyl 2-bromoisonicotinate
Referemce:
Pyridine – Wikipedia,
Pyridine | C5H5N – PubChem