Supramolecular recognition: Protonmotive-driven switches or motors? was written by Crowley, James D.;Goshe, Andrew J.;Steele, Ian M.;Bosnich, Brice. And the article was included in Chemistry – A European Journal in 2004.COA of Formula: C6H6N2O3 This article mentions the following:
A dicationic mol. receptor bearing two cofacially disposed terpyridyl-Pd-Cl units forms stable 1:1 host-guest complexes with planar, neutral Pt(II) complexes. When the guest is modified to incorporate a pyridine group, the now basic guest is protonated by HO2CCF3 in MeCN solutions The basic yellow guest forms a stable, deep red 1:1 host-guest complex with the yellow Pd receptor. Addition of HO2CCF3 to this host-guest complex leads to the displacement of the guest from the receptor. Probably the dissociation of the guest is caused by electrostatic repulsion between the dicationic receptor and the pos. charged protonated guest. Addition of base restores the host-guest complex. This protonmotive translocation of the guest from the host to the solution is discussed in terms of the mechanisms that drive mol. motors, the power stroke and the Brownian ratchet. The system is best described as a mol. switch that operates by the same mechanism as one stroke of a mol. motor. The mol. structures of a dipalladium(II) host and of a platinum(II) ammine O-N-O Schiff base chelate were determined by x-ray crystallog. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2COA of Formula: C6H6N2O3).
3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.COA of Formula: C6H6N2O3