Rearrangement of N,N-Di-tert-butoxycarbonylpyridin-4-amines and Formation of Polyfunctional Pyridines was written by Liu, Yahua;Ding, Qiang;Wu, Xu. And the article was included in Journal of Organic Chemistry in 2008.Reference of 209798-48-1 This article mentions the following:
N,N-Di-tert-butoxycarbonylpyridin-4-amines I (R1 = R2 = Cl; R1 = Cl, Br, tert-Bu, R2 = H) were found to be rearranged to tert-Bu 4-(tert-butoxycarbonylamino)nicotinates II by treatment with LDA in THF. In the experiment, the researchers used many compounds, for example, (2-Chloro-pyridin-3-yl)-carbamic acid tert-butyl ester (cas: 209798-48-1Reference of 209798-48-1).
(2-Chloro-pyridin-3-yl)-carbamic acid tert-butyl ester (cas: 209798-48-1) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Reference of 209798-48-1