Polystyrene supported Dichloro-(8-aminoquinoline)-Palladium(II) complex catalyzed C-H bond activation for ortho-acylation of 2-aryl pyridines was written by Perumgani, C. Pullaiah;Parvathaneni, Sai Prathima;Kodicherla, Balaswamy;Keesara, Srinivas;Mandapati, Mohan Rao. And the article was included in Inorganica Chimica Acta in 2017.Computed Properties of C12H11N This article mentions the following:
Polystyrene-supported Dichloro-(8-aminoquinoline)-Pd(II) complex C was synthesized and its catalytic efficiency was evaluated for ortho-acylation of 2-arylpyridines with alcs. to form aryl ketones via cross dehydrogenative coupling [e.g., 2-phenylpyridine + benzyl alc. → 2-(2-pyridyl)benzophenone (91%)]. In addition in the presence of Pd(II) complex, toluene derivatives were also employed as an effective coupling partner for synthesis of aromatic ketones. Furthermore, this catalyst was highly stable and could be easily recovered by simple filtration and reused for four cycles with no significant decrease in its activity and selectivity. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Computed Properties of C12H11N).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Computed Properties of C12H11N