Rhodium-Catalyzed Synthesis of Multiaryl-substituted Naphthols via a Removable Directing Group was written by Wang, Lianhui;Yu, Yunliang;Yang, Mengqi;Kuai, Changsheng;Cai, Dingding;Yu, Jinfeng;Cui, Xiuling. And the article was included in Advanced Synthesis & Catalysis in 2017.SDS of cas: 4783-68-0 This article mentions the following:
Arene homologation employing internal alkynes ArCCAr (Ar = 4-methylphenyl, 3-fluorophenyl, 4-acetylphenyl, etc.) as coupling partners and 2-pyridyloxyl as directing group through dual C-H bond functionalization was accomplished using (pentamethylcyclopentadienyl)-rhodium(III) chloride dimer as a pre-catalyst. This protocol proved tolerant of synthetically valuable functional groups, and provided an expeditious access to highly congested naphthalene derivatives, e.g., I in moderate to good yields. Furthermore, the pyridyl moiety could be removed to furnish the versatile (OH)-free naphthols II (Ar = Ph, 3-fluorophenyl; R = H, 2-Me, 3-Me, 4-F). In the experiment, the researchers used many compounds, for example, 2-Phenoxypyridine (cas: 4783-68-0SDS of cas: 4783-68-0).
2-Phenoxypyridine (cas: 4783-68-0) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Several pyridine derivatives play important roles in biological systems. While its biosynthesis is not fully understood, nicotinic acid (vitamin B3) occurs in some bacteria, fungi, and mammals.SDS of cas: 4783-68-0