Cu(
A protocol for the hydroxylation of aryl halides catalyzed by copper(I) and sucrose in neat water was developed. The dual role of sucrose, the reaction pathway, and the high selectivity for hydroxylation were investigated using a combination of exptl. and theor. techniques. In the experiment, the researchers used many compounds, for example, 5-Hydroxy-2-methoxylpyridine (cas: 51834-97-0SDS of cas: 51834-97-0).
5-Hydroxy-2-methoxylpyridine (cas: 51834-97-0) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.SDS of cas: 51834-97-0