Synthesis of 3-pyridylpropenoic acid esters via Heck coupling of substituted 3-pyridyl triflates was written by Draper, Tandy L.;Bailey, Thomas R.. And the article was included in Synlett in 1995.Related Products of 15128-90-2 This article mentions the following:
From com. available 3-hydroxypyridines, several 3-pyridinepropenoic Et esters were prepared in good yield via Heck coupling of Et acrylate and the pyridyl triflate. In general, LiCl accelerated the coupling, but was not required for all reactions. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2Related Products of 15128-90-2).
3-Hydroxy-6-methyl-2-nitropyridine (cas: 15128-90-2) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Related Products of 15128-90-2