Copper(II) mediated C-H methylthiolation of 2-phenyl pyridines with dimethyl sulfoxide using an amino acid ligand was written by Xiao, Yan;Wang, Shuo;Liu, Jianyu;Zhang, Hui;Xu, Yongnan. And the article was included in Tetrahedron Letters in 2019.Quality Control of 2-(m-Tolyl)pyridine This article mentions the following:
A novel protocol for the C-H methylthiolation of 2-Ph pyridines using DMSO as the methylthio source and an amino acid ligand was described. This simple procedure doesn’t requires neither an oxidant nor an addnl. solvent. The developed protocol tolerates a wide range of functional groups including Me, methoxy, fluoro, chloro and in particular the formyl group. This new strategy is highly regioselective and provided aryl Me sulfides from 2-Ph pyridines in moderate to good yields. In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Quality Control of 2-(m-Tolyl)pyridine).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine has a conjugated system of six π electrons that are delocalized over the ring. The molecule is planar and, thus, follows the Hückel criteria for aromatic systems. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Quality Control of 2-(m-Tolyl)pyridine