Reactions of pyridinium salts and pyridine bases. V. Synthesis of γ-alkoxy-, -alkylmercapto-, and -alkyl-substituted pyridines was written by Vompe, A. F.;Monich, N. V.;Meskhi, L. M.. And the article was included in Zhurnal Organicheskoi Khimii in 1974.HPLC of Formula: 27876-24-0 This article mentions the following:
4-Phenoxypyridine (I) condensed with NaOR (R = Me, Et, Me2CH, Bu, Me2CHCH2CH2, cyclohexyl, 1-dodecyl) at 110-70° to give the corresponding alkoxypyridines II in 83-97% yields. Similarly, I and NaSR1 (R1 = Et, Pr, Bu, hexyl) gave the (alkylthio)pyridines III. I and R2MgX (R2 = alkyl, isoalkyl, cycloalkyl; X = Br, Cl, iodide) were heated at 115-190° in a N atm. for 3-10 hr to give the alkylpyridines IV. In the experiment, the researchers used many compounds, for example, 4-Hexylpyridine (cas: 27876-24-0HPLC of Formula: 27876-24-0).
4-Hexylpyridine (cas: 27876-24-0) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.HPLC of Formula: 27876-24-0