Reaction of 3-substituted and 3,5-disubstituted pyridine N-oxides with phenyl isocyanate was written by Hisano, Takuzo;Matsuoka, Toshikazu;Ichikawa, Masataka. And the article was included in Organic Preparations and Procedures International in 1974.Electric Literature of C7H9NO This article mentions the following:
3,5-Dimethylpyridine N-oxide was treated with PhNCO to give I, which was hydrolyzed to give 2-anilino-3,5-dimethylpyridine. 3-Bromopyridine and PhNCO gave 46% oxazolopyridinone II, 3% 2-anilino-3-bromopyridine, and 3% 6-anilino-3-bromopyridine. In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Electric Literature of C7H9NO).
3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Electric Literature of C7H9NO