One-Step Conversion of Azine N-Oxides to α-1,2,4-Triazolo-, 1,2,3-Triazolo, Imidazolo-, and Pyrazoloheteroarenes was written by Keith, John M.. And the article was included in Journal of Organic Chemistry in 2010.Product Details of 3718-65-8 This article mentions the following:
Pyridine, quinoline, isoquinoline, azaindole, and pyrimidine N-oxides, e.g. I, were converted to their α-triazole and α-diazole derivatives, e.g. II, by treatment with the corresponding p-toluenesulfonylazoles and Hunig’s base at elevated temperatures In the experiment, the researchers used many compounds, for example, 3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8Product Details of 3718-65-8).
3,5-Dimethylpyridine 1-oxide (cas: 3718-65-8) belongs to pyridine derivatives. In contrast to benzene, Pyridine’s electron density is not evenly distributed over the ring, reflecting the negative inductive effect of the nitrogen atom. Many analogues of pyridine are known where N is replaced by other heteroatoms . Substitution of one C–H in pyridine with a second N gives rise to the diazine heterocycles (C4H4N2), with the names pyridazine, pyrimidine, and pyrazine.Product Details of 3718-65-8