Synthesis of 4-methoxy and 5-methoxy substituted 7-aza-isoindolin-1-ones was written by Zhou, Heng;Sun, Guanglong;Liu, Zenglu;Zhan, Xiaoping;Mao, Zhenmin. And the article was included in Heterocycles in 2013.Application of 59718-84-2 This article mentions the following:
A simple and convenient route for the synthesis of a series of 4-methoxy or 5-methoxy substituted 7-aza-isoindolin-1-ones is described. Methoxyl substituted pyridine derivatives were cyclized with different amines under alk. condition to give the desired products. In the experiment, the researchers used many compounds, for example, Methyl 3-methylpicolinate (cas: 59718-84-2Application of 59718-84-2).
Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. Pyridines are an important class of heterocycles and occur in polysubstituted forms in many naturally occurring biologically active compounds, drug molecules and chiral ligands. Reduced pyridines, namely tetrahydropyridines, dihydropyridines and piperidines, are found in numerous natural and synthetic compounds. The synthesis and reactivity of these compounds have often been driven by the fact many of these compounds have interesting and unique pharmacological properties. Application of 59718-84-2