Synthesis of new thiopyranopyridines was written by Dunn, A. D.. And the article was included in Journal fuer Praktische Chemie (Leipzig) in 1987.Formula: C8H9NO2 This article mentions the following:
Thiopyranopyridinecarboxylates I and II (X, Y = CH, N; R = OH, NH2) are prepared from pyridine esters (e.g., III; R1 = Me, R2 = CO2Me; R1 = CO2Me, R2 = Me) and nitriles (e.g., III; R1 = Me, R2 = CN) by photochem. bromination, followed by substitution reaction of the resulting bromomethyl derivative with HSCH2CO2Me, and then base-induced intramol. cyclocondensation. In the experiment, the researchers used many compounds, for example, Methyl 3-methylpicolinate (cas: 59718-84-2Formula: C8H9NO2).
Methyl 3-methylpicolinate (cas: 59718-84-2) belongs to pyridine derivatives. Pyridine is diamagnetic and has a diamagnetic susceptibility of −48.7 × 10−6 cm3·mol−1.The molecular electric dipole moment is 2.2 debyes. The standard enthalpy of formation is 100.2 kJ·mol−1 in the liquid phase and 140.4 kJ·mol−1 in the gas phase. Halopyridines are particularly attractive synthetic building blocks in a variety of cross-coupling methods, including the Suzuki-Miyaura cross-coupling reaction.Formula: C8H9NO2