Co-crystallization of oxadiazole-bridged pyridyl-N-oxide building modules with R-aromatics (R = -OH, -NH2 and -COOH) was written by Hou, Gui-Ge;Ma, Jian-Ping;Wang, Le;Wang, Ping;Dong, Yu-Bin;Huang, Ru-Qi. And the article was included in CrystEngComm in 2010.Application of 15420-02-7 This article mentions the following:
The reaction of oxadiazole bridging pyridyl-N-oxides (2,5-bis(4-pyridyl-N-oxide)-1,3,4-oxadiazole (A1) and 2-(4-pyridyl)-5-(4-pyridyl-N-oxide)-1,3,4-oxadiazole (A2)) with different substituted aromatics (R-aromatics, R = -OH, -NH2, -COOH) were studied. Eight new organic co-crystals of 1-8 were synthesized and characterized by elemental anal., FTIR spectroscopy, 1H NMR and single-crystal x-ray diffraction. The results display the distinct substituent effect on the hydrogen-bonded self-assembly systems. The luminescent properties of A1-A2 and 1-8 were studied in the solid state. In the experiment, the researchers used many compounds, for example, 2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7Application of 15420-02-7).
2,5-Di(pyridin-4-yl)-1,3,4-oxadiazole (cas: 15420-02-7) belongs to pyridine derivatives. The ring atoms in the pyridine molecule are sp2-hybridized. The nitrogen is involved in the π-bonding aromatic system using its unhybridized p orbital. The lone pair is in an sp2 orbital, projecting outward from the ring in the same plane as the σ bonds. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Application of 15420-02-7