Anion-Controlled Cation-Exchange Process: Intercalating α-Titanium Phosphate through Direct Ion Exchange with Alkylammonium Salts was written by Wang, Chunyang;Cheng, Qingyan;Wang, Yanji. And the article was included in Inorganic Chemistry in 2018.Formula: C5H6ClN This article mentions the following:
Several alkylammonium salts were used in the study of α-titanium phosphate (α-TiP) intercalation chem. The characterization results demonstrated that the expected intercalation by direct ion exchange could be successfully achieved without any addition of an extra amine substance. The authors’ findings are different from the current opinion that by the ion-exchange method, without the assistance of bases, large cations are difficult to exchange into the narrow interlayer space of α-tetravalent metal phosphate directly because of the small interlayer distance. Studies found that alkylammonium cations, for example, n-butylammonium cation, could be directly exchanged into the interlayer space merely by choosing salts with appropriate anions such as phosphate, phosphite, sulfite, citrate, and malate ions. In the case of phosphates, besides n-butylammonium, the exchange of n-hexylammonium, cyclohexylammonium, and pyridinium with interlayer protons was studied and successfully accomplished as well. The uptake values for these four cations were 0.420, 0.595, 0.571, and 0.335 g/g, resp. A mechanism study revealed that although the relevant exchange reaction seemed only to involve the proton of α-TiP and the alkylammonium cation of the salt, the strength of the conjugate acid of the anion from the salt-the counterion-was proven to be the key factor in this process. In the experiment, the researchers used many compounds, for example, Pyridinehydrochloride (cas: 628-13-7Formula: C5H6ClN).
Pyridinehydrochloride (cas: 628-13-7) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. Pyridine derivatives are also useful as small-molecule α-helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.Formula: C5H6ClN