Rh(III)-Catalyzed Regioselective Acetylation of sp2 C-H Bond Starting from Paraformaldehyde was written by Wan, Ting;Du, Sidong;Pi, Chao;Wang, Yong;Li, Rongbin;Wu, Yangjie;Cui, Xiuling. And the article was included in ChemCatChem in 2019.Related Products of 4373-61-9 This article mentions the following:
Rh(III)-catalyzed acetylation of sp2 C-H bonds has been realized using paraformaldehyde as an acetylating reagent. This procedure features simultaneous formation of two C-C bonds, external oxidants free, and water as the sole byproducts, thus offering an environmentally benign acetylation of arenes R1R2 (R1 = pyridin-2-yl, 4-methylpyridin-2-yl, isoquinolin-1-yl; R2 = Ph, 3-bromophenyl, 2,3-dihydro-1,4-benzodioxin-5-yl, etc.). A range of functional groups tolerance was observed In the experiment, the researchers used many compounds, for example, 2-(m-Tolyl)pyridine (cas: 4373-61-9Related Products of 4373-61-9).
2-(m-Tolyl)pyridine (cas: 4373-61-9) belongs to pyridine derivatives. Pyridine’s the lone pair does not contribute to the aromatic system but importantly influences the chemical properties of pyridine, as it easily supports bond formation via an electrophilic attack. One of the examples of pyridines is the well-known alkaloid lithoprimidine, which is an A3 adenosine receptor antagonist and N,N-dimethylaminopyridine (DMAP) analog, commonly used in organic synthesis.Related Products of 4373-61-9