Direct Synthesis of N-Difluoromethyl-2-pyridones from Pyridines was written by Zhou, Sen;Hou, Xiaoya;Yang, Kai;Guo, Minjie;Zhao, Wentao;Tang, Xiangyang;Wang, Guangwei. And the article was included in Journal of Organic Chemistry in 2021.HPLC of Formula: 626-64-2 This article mentions the following:
A novel method for the synthesis of N-difluoromethyl-2-pyridones was described. This protocol enables the synthesis of N-difluoromethyl-2-pyridones from readily available pyridines using mild reaction conditions that are compatible with a wide range of functional groups. The preliminary mechanistic study revealed that N-difluoromethylpyridinium salts were the key intermediates to complete this conversion. In the experiment, the researchers used many compounds, for example, Pyridin-4-ol (cas: 626-64-2HPLC of Formula: 626-64-2).
Pyridin-4-ol (cas: 626-64-2) belongs to pyridine derivatives. The pyridine ring occurs in many important compounds, including agrochemicals, pharmaceuticals, and vitamins. Pyridine derivatives are also useful as small-molecule 浼?helix mimetics that inhibit protein-protein interactions, as well as functionally selective GABA ligands.HPLC of Formula: 626-64-2